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Reproductive Physiology

E. Keith Inskeep

headshot of Keith Inskeep

Professor Emeritus

Division of Animal & Nutritional Sciences 
P.O. Box 6108 
Davis College of Agriculture, Natural Resources and Design 
West Virginia University 
2109 Agricultural Sciences
304-293-1936 
einskeep@wvu.edu

EDUCATION

PhD, University of Wisconsin, Endocrinology, 1964 
MS, University of Wisconsin, Genetics, 1960 
BS, West Virginia University, Dairy Science 1959 
AA, Potomac State College, Agriculture 1957

RESEARCH AND PROFESSIONAL INTERESTS

State 140 – Increasing Farm Income By A Strategic Shift In Breeding Time For Ewe Flocks – Funded by WV Legislature 
Hatch 476 (NE 1227) – Ovarian Influences on Reproductive Success in Ruminants

ANNUAL TEACHING

Animal Physiology 424 – Reproductive Physiology of Farm Animals, Spring Semester, Team Taught, annually, 3 hours 
Animal Physiology 726 – Endocrinology of Reproduction Spring Semester, alternate years, 4 hours 
Animal Physiology 794 – Reproductive Physiology Seminar, Every Semester, 1 hour 
Animal Production 356 – Small Ruminant Production, alternate years, 3 hours 
Animal & Veterinary Sciences 493 – Lambing Management, Spring Semester, 1 hour

REPRESENTATIVE PUBLICATIONS

Goodman, R. L. and  E. K. Inskeep. 2014. Control of the Ovarian Cycle of the Sheep. Chapter 28 in Knobil and Neill’s Physiology of Reproduction. Edited by Tony Plant and Tony Zeleznik, 47 pages (In Press). 

Holler, Tammy L., Matthew Dean, Todd Taylor, Daniel H. Poole, M. L. Thonney, D. L. Thomas, J. L. Pate, N. Whitley, R. A. Dailey, and  E. K. Inskeep. 2014. Effects of service sire on prenatal mortality and prolificacy in ewes. J. Anim. Sci. jas.2013-7489; published ahead of print April 28, 2014, doi:10.2527/jas.2013-7489 

Wright, M. F., E. Bowdridge, E. L. McDermott, S. Richardson, J. Scheidler,  E. K. Inskeep and J. A. Flores. 2014. Mechanisms of intracellular calcium homeostasis in the developing and mature bovine corpora lutea. Biol. Reprod. 90:1-12. 

Inskeep, E. K. and R. L. Goodman. 2013. Factors that affect prolificacy in sheep. Proceedings, Western Section, Am. Soc. Anim. Sci. 64:19-23. 

Ganchou, F. P., J. E. Mankey, M. P.Goravanahally,  E. K. Inskeep and J. A. Flores. 2012. Effect of chronic administration of endothelin receptor type a antagonist (bq-610) on functional lifespan of the corpus luteum in sheep. Revista Científica, FCV-LUZ 22:321–331. 

Inskeep, E.K. 2011. Ruminant reproduction: recent findings and future challenges, a summary. In: Reproduction in Domestic Ruminants VII. M.F. Smith, M. Lucy and T. Spencer, Eds. 12 pp. 

Inskeep, E.K. 2010. Time-dependent embryotoxicity of the endogenous luteolysin prostaglandin F2α in ruminants. Chapter 10, pp 240-255 in Endocrine Toxicology. C. Eldridge and J.T. Stevens, Eds. Informa Healthcare, London. 

Inskeep, E.K. and R.A. Dailey 2010. Maximizing embryonic and early fetal survival in dairy cattle. In WCDS Advances in Dairy Technology 22:51-69. Lorraine Doepel, Editor. 

Jordan, K.M.,  E.K. Inskeep, M. Knights. 2009. Use of gonadotropin releasing hormone to improve reproductive responses of ewes introduced to rams during seasonal anestrus. Anim.. Reprod. Sci. 116 (2009):254-264. 

Doerr, M. D, M. P. Goravanahally, J. D. Rhinehart,  E. K. Inskeep and J. A. Flores. 2008. Effects of endothelin receptor type-A and type-B antagonists on prostaglandin F2a-induced luteolysis of the sheep corpus luteum Biol. Reprod. 78:688-696. 

Stevenson, J. S., S. M. Tiffany and  E. K. Inskeep. 2008. Maintenance of pregnancy in dairy cattle after treatment with human chorionic gonadotropin or gonadotropin-releasing hormone. J. Dairy Sci. 91:3092–3101. 

Dixon, A. B. M. Knights, J. L. Winkler, D. J. Marsh, J. L. Pate, M. E. Wilson, R. A. Dailey, G. Seidel and  E. K. Inskeep. 2007. Patterns of late embryonic and fetal mortality and association with several factors in sheep. J. Anim. Sci. 85:1274-1284. 

Lingenfelter, B. M., R. A. Dailey,  E. K. Inskeep, M. W. Vernon, D. H. Poole, J. D. Rhinehart, and J. Yao. 2007. Changes of maternal transcripts in oocytes from persistent follicles in cattle. Molecular Reproduction and Development 74: 265-272. 

Starbuck, M. J., R. A. Dailey and  E. K. Inskeep. 2004. Factors affecting retention of early pregnancy in cattle. Anim. Reprod. Sci. 84:27-39. 

Inskeep, E. K. 2004. Preovulatory, postovulatory, and post- maternal recognition effects of concentrations of progesterone on embryonic survival in the cow. J. Anim. Sci. 82(E. Suppl.):E24E39. 

Sen, A., J. Browning,  E. K. Inskeep, P. Lewis, and J. A. Flores. 2004. Expression and activation of protein kinase C isozymes by prostaglandin F2 in the early- and mid-luteal phase bovine corpus luteum. Biol Reprod 70:379-384. 

Starbuck, M. J., R. A. Dailey and  E. K. Inskeep. 2004. Factors affecting retention of early pregnancy in cattle. Anim. Reprod. Sci. 84:27-39. 

Inskeep, E. K. 2004. Preovulatory, postovulatory, and post- maternal recognition effects of concentrations of progesterone on embryonic survival in the cow. J. Anim. Sci. 82(E. Suppl.):E24E39. 

Choudhary, E., B. A. Costine, M. E. Wilson,  E. K. Inskeep and J. A. Flores. 2004. Prostaglandin F2 (PGF2)-independent and -dependent regulation of the bovine luteal endothelin system. Dom. Anim. Endo. 27:63-69.